Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EHMT2' and Ligand = 'BDBM50457746'
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50457746(CHEMBL4208004)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of G9a (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50457746(CHEMBL4208004)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human G9a enzyme using histone monomethyl-H3K9 peptide as substrate incubated for 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9V8VPubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50457746(CHEMBL4208004)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05CMPubMed