Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12' and Ligand = 'BDBM451072'
LigandPNGBDBM451072(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)- |...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM451072(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)- |...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM451072(N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)- |...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent