Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2' and Ligand = 'BDBM50574994'
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM50574994(CHEMBL4847620)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of EZH2 (unknown origin) using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44V3JPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM50574994(CHEMBL4847620)copy SMILES
Affinity DataKd:  0.0693nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as dissociation rate constant using H3K27me0 peptide substrate incubated for 3 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44V3JPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM50574994(CHEMBL4847620)copy SMILES
Affinity DataKd:  21nMAssay Description:Inhibition of recombinant PRC2 complex (unknown origin) assessed as kd/ka using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44V3JPubMed