Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Hydroxysteroid 11-beta dehydrogenase 1' and Ligand = 'BDBM50273458'
TargetHydroxysteroid 11-beta dehydrogenase 1(Canis familiaris)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50273458((5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of dog recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GN7PubMed
TargetHydroxysteroid 11-beta dehydrogenase 1(Canis familiaris)
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50273458((5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of dog 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GN7PubMed