Found 4 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM370456' TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bayer HealthCare Pharmaceuticals Corporation
Bayer HealthCare Pharmaceuticals Corporation
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bayer HealthCare Pharmaceuticals Corporation
Bayer HealthCare Pharmaceuticals Corporation
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bayer HealthCare Pharmaceuticals Corporation
Bayer HealthCare Pharmaceuticals Corporation
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bayer HealthCare Pharmaceuticals Corporation
Bayer HealthCare Pharmaceuticals Corporation
Affinity DataEC50: 3.10E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in T-REx-293 cells assessed as reduction in kynurenine level measured after 16 hrsMore data for this Ligand-Target Pair
