Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50138830'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bayer HealthCare Pharmaceuticals Corporation

LigandPNGBDBM50138830(CHEMBL3752659 | US10233190, Example 1415)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4KQMUS Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bayer HealthCare Pharmaceuticals Corporation

LigandPNGBDBM50138830(CHEMBL3752659 | US10233190, Example 1415)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in M15(pREP4) cells using L-tryptophan as substrate assessed as conversion of N-formylkynurenine to ky...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28917QWPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bayer HealthCare Pharmaceuticals Corporation

LigandPNGBDBM50138830(CHEMBL3752659 | US10233190, Example 1415)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed