Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50514760'
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human MCF7 cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Universit£ del Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human DAN-G cells assessed as reduction in L-Kyn level measured after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4FKSPubMed