Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50578624'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578624(CHEMBL4856710)copy SMILES
Affinity DataIC50: 0.600nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)TBA
LigandPNGBDBM50578624(CHEMBL4856710)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50578624(CHEMBL4856710)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of IDO1 in human whole blood stimulated with IFNgamma/LPS using L-tryptophan/kynurenine as substrate incubated for 15 mins followed by IFN...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)TBA
LigandPNGBDBM50578624(CHEMBL4856710)copy SMILES
Affinity DataIC50: 25nMAssay Description:In vivo inhibition of IDO1 in tumor of po dosed NSG mouse xenografted with human SKOV3 cells assessed as reduction in KYN level administered as singl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P9SPubMed