Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM50303503'
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50303503(CHEMBL4160782 | US10858316, Compound SF-5-141)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Inhibition of FITC-BAK binding to His6 tagged MBP fused recombinant human MCL1 (172 to 327 residues) expressed in Escherichia coli by fluorescence po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6VS2PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50303503(CHEMBL4160782 | US10858316, Compound SF-5-141)copy SMILEScopy InChI
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
In DepthDetails
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50303503(CHEMBL4160782 | US10858316, Compound SF-5-141)copy SMILEScopy InChI
Affinity DataKi:  286nMAssay Description:Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9SHVUS Patent