Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Inhibitor of nuclear factor kappa-B kinase subunit alpha' and Ligand = 'BDBM28545'
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMT: 2°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB804MPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5GZDPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of IKK1-catalyzed phosphorylation of GST-tagged IkappaBalpha fusion protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SX8PubMed