Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Inhibitor of nuclear factor kappa-B kinase subunit beta' and Ligand = 'BDBM50507359'
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.

Curated by ChEMBL
LigandPNGBDBM50507359(CHEMBL4529539)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human C-terminal GST-tagged IKKbeta (1 to 737 residues) expressed in baculovirus expression system using GST-IkBalpha subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1V1HPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.

Curated by ChEMBL
LigandPNGBDBM50507359(CHEMBL4529539)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of IKKbeta in human CD14-positive monocytes assessed as reduction in LPS-stimulated TNFalpha secretion preincubated for 30 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1V1HPubMed