Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Inosine-5'-monophosphate dehydrogenase 2' and Ligand = 'BDBM19269'
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM19269(Acridone-Based Inhibitor, 8a | N-tert-butyl-9-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 59nM EC50:  3.30E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58JPVPubMed