Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50230005'
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R autophosphorylationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of IGF1R-dependent tumor cell growth in human MCF7 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of IGF1R autophosphorylation in human MCF7 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of IGF1R autophosphorylation in human MCF7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of IGF1R-dependent tumor cell growth in human MCNeuA cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of recombinant IGF1R by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27944WQPubMed