Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50296357'
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6ZPBPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of IGF1R-mediated colony formation in human LNCaP cells after 12 days by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6ZPBPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of IGF1R-mediated colony formation in human MCF7 cells after 12 days by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6ZPBPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of IGF1R-mediated colony formation in human PC3 cells after 12 days by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6ZPBPubMed