Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Integrase' and Ligand = 'BDBM107693'
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7HDKPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 recombinant integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7HDKPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BR1PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TPDPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TPDPubMed