Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Integrase' and Ligand = 'BDBM50115572'
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/NIH

Curated by ChEMBL
LigandPNGBDBM50115572((Z)-4-(3-Benzyloxy-phenyl)-2-hydroxy-4-oxo-but-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TPDPubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/NIH

Curated by ChEMBL
LigandPNGBDBM50115572((Z)-4-(3-Benzyloxy-phenyl)-2-hydroxy-4-oxo-but-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3CB7PubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/NIH

Curated by ChEMBL
LigandPNGBDBM50115572((Z)-4-(3-Benzyloxy-phenyl)-2-hydroxy-4-oxo-but-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BR1PubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/NIH

Curated by ChEMBL
LigandPNGBDBM50115572((Z)-4-(3-Benzyloxy-phenyl)-2-hydroxy-4-oxo-but-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of Integrase (3'-processing) as measured in an in vitro assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8628PubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/NIH

Curated by ChEMBL
LigandPNGBDBM50115572((Z)-4-(3-Benzyloxy-phenyl)-2-hydroxy-4-oxo-but-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assay in experiment 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TPDPubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/NIH

Curated by ChEMBL
LigandPNGBDBM50115572((Z)-4-(3-Benzyloxy-phenyl)-2-hydroxy-4-oxo-but-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibitory concentration against Recombinant HIV-1 integrase (Standard transfer reaction)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3CB7PubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/NIH

Curated by ChEMBL
LigandPNGBDBM50115572((Z)-4-(3-Benzyloxy-phenyl)-2-hydroxy-4-oxo-but-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assay in experiment 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TPDPubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/NIH

Curated by ChEMBL
LigandPNGBDBM50115572((Z)-4-(3-Benzyloxy-phenyl)-2-hydroxy-4-oxo-but-2-e...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration of the compound was determined against Recombinant HIV-1 integrase (3'processing)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3CB7PubMed