Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Integrin alpha-L' and Ligand = 'BDBM50318231'
TargetIntegrin alpha-L(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50318231(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP82B4PubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50318231(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of LFA1-mediated human T cell proliferation assessed as [3H]thymidine uptake after 4 days by mixed lymphocyte reaction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP82B4PubMed