Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50126594'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Binding affinity for alphaV-beta5 vitronectin receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15K8PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human intergrin alphavbeta3 receptor by solid phase receptor assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FK0PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human intergrin alphavbeta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FK0PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126594(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of HEK 293 cell adhesion to vitronectin by human alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FN15K8PubMed