Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM50262366'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Discovery Chemistry, Research& Development, Bristol-Myers Squibb Company, Route 206& Province Line Road, Princeton, NJ 08543, United States. Electronic address: bhider09@gmail.com.

Curated by ChEMBL
LigandPNGBDBM50262366(CHEMBL4079743)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluorescent labelled IPTSPITTTYFFFKKK peptide as substrate after 60 mins by caliper assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Discovery Chemistry, Research& Development, Bristol-Myers Squibb Company, Route 206& Province Line Road, Princeton, NJ 08543, United States. Electronic address: bhider09@gmail.com.

Curated by ChEMBL
LigandPNGBDBM50262366(CHEMBL4079743)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of IRAK4 (unknown origin) using FL-IPTSPITTTYFFFKKK peptide and ATP as substrate incubated for 60 mins by fluorescence based caliper assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Discovery Chemistry, Research& Development, Bristol-Myers Squibb Company, Route 206& Province Line Road, Princeton, NJ 08543, United States. Electronic address: bhider09@gmail.com.

Curated by ChEMBL
LigandPNGBDBM50262366(CHEMBL4079743)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of IRAK4 in human PBMC assessed as inhibition of LTA-induced IL-6 production preincubated for 30 mins followed by LTA-stimulation and meas...More data for this Ligand-Target Pair