Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Interleukin-2' and Ligand = 'BDBM387290'
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387290(N-(5- (5,5-Dimethyl-4,5- dihydroisoxazol-3- yl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 328nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82F4QPubMed
TargetInterleukin-2(Homo sapiens (Human))TBA
LigandPNGBDBM387290(N-(5- (5,5-Dimethyl-4,5- dihydroisoxazol-3- yl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q8BUS Patent