Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'Interstitial collagenase' and Ligand = 'BDBM50082556'
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4XH4PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T0BPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of collagenase-1 (Matrix metalloprotease-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D79C32PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataKi:  8.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D79C32PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP747BPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34Z6TPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibitory activity against MMP-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HM57NSPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5H6ZPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11FFPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KD9PubMed