Found 2 Enz. Inhib. hit(s) with Target = 'Isocitrate dehydrogenase [NADP], mitochondrial' and Ligand = 'BDBM247859' TargetIsocitrate dehydrogenase [NADP], mitochondrial(Homo sapiens (Human))
Saint Petersburg State University
Curated by ChEMBL
Saint Petersburg State University
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of IDH2 R140Q mutant (unknown origin) expressed in human HCT116 cells assessed as reduction in 2-HG levelMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Homo sapiens (Human))
Saint Petersburg State University
Curated by ChEMBL
Saint Petersburg State University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IDH2 R172K mutant (unknown origin) expressed in human HCT116 cells assessed as reduction in 2-HG levelMore data for this Ligand-Target Pair
