Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Isocitrate dehydrogenase [NADP] cytoplasmic' and Ligand = 'BDBM146000'
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM146000(US8957068, 35)copy SMILEScopy InChI
Affinity DataIC50: 248nMpH: 7.4 T: 2°CAssay Description:Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9W28US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM146000(US8957068, 35)copy SMILEScopy InChI
Affinity DataIC50: 250nMMore data for this Ligand-Target Pair
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM146000(US8957068, 35)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails