BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = 'Isocitrate dehydrogenase [NADP] cytoplasmic' and Ligand = 'BDBM279977'

Isocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Agios Pharmaceuticals, Inc.

Curated by ChEMBL

BDBM279977(US10028961, Compound 130 | US10172864, Compound 13...)copy SMILEScopy InChI

IC50: 0.300nMAssay Description:Inhibition of IDH1 R132H mutant in glioma patient-derived human TS603 neurosphere cells assessed as reduction in 2-HG content using alpha-ketoglutara...More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase PC cid PC sid PDB

Details Article
BindingDB Entry DOI: 10.7270/Q28G8Q0NPubMed PDB

3D Structure (crystal)