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TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Saint Petersburg State University
Curated by ChEMBL
Saint Petersburg State University
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Saint Petersburg State University
Curated by ChEMBL
Saint Petersburg State University
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of IDH1 R132H mutant in human HCT116 cells assessed as reduction in 2-HG level after 48 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
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