Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Isocitrate dehydrogenase [NADP] cytoplasmic' and Ligand = 'BDBM50550471'
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))TBA
LigandPNGBDBM50550471(CHEMBL4763449)copy SMILES
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))TBA
LigandPNGBDBM50550471(CHEMBL4763449)copy SMILES
Affinity DataIC50: 8.50E+3nMAssay Description:Allosteric inhibition of IDH1 R132H mutant (unknown origin) expressed in HEK293T cells assessed as reduction in 2-HG production incubated for 48 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed