Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)' and Ligand = 'BDBM109236'
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia

LigandPNGBDBM109236(WEHI-539)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7FZ7PubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia

LigandPNGBDBM109236(WEHI-539)copy SMILEScopy InChI
Affinity DataIC50: 7.10nM Kd:  1.40nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7FZ7PubMed