Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM156575'
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156575(US10118915, Compound 355 | US9682966, 355)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2610XHQUS Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156575(US10118915, Compound 355 | US9682966, 355)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3G00US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156575(US10118915, Compound 355 | US9682966, 355)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at GAL4-VP16-fused KOR (unknown origin) expressed in human U2OS cells co-expressing Tango-OPRK1-BLA assessed as inhibition of U-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4N6QPubMed