Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50010702'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3G7FPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z42X1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3BH2PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataIC50: 0.231nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain homogenate using [3H]- U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB51XHPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
SRI International

Curated by PDSP Ki Database
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataIC50: 0.231nMAssay Description:Inhibition of [3H]-U-69,593 binding to kappa opoid receptor of guinea pig brain homogenateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936K7PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataEC50:  0.410nMAssay Description:Agonist activity at human KOR expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by luminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38V6PPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human kappa opioid receptor transfected in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3G7FPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor Corporation

Curated by ChEMBL
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)copy SMILEScopy InChI
Affinity DataEC50:  6.30nMAssay Description:Antagonist activity at human recombinant kappa opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of dynorphin A-ind...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445NQDPubMed