Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50068379'
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50068379(5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Effect on binding affinity of mutational exchange of Glu297 in the Opioid receptor kappa 1 in transiently expressed rat cos-7 cells activity expresse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50068379(5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...)copy SMILEScopy InChI
Affinity DataKi:  0.290nMAssay Description:Mutant factor against mu-[K303E] with Opioid receptor kappa 1 for binding affinityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50068379(5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Mutant factor of the compound against kappa[E297K] with Opioid receptor kappa 1 for binding affinity.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9387KPubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50068379(5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...)copy SMILEScopy InChI
Affinity DataKi:  4.46nMAssay Description:Binding affinity on HEK-293 cells transiently transfected with plasmids encoding the rat Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4W2WPubMed