Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50097579'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097579((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X87JZPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097579((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RCTPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097579((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208663GPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50097579((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)copy SMILEScopy InChI
Affinity DataKi:  0.420nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959G3PPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50097579((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB529VPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Rochester

Curated by PDSP Ki Database
LigandPNGBDBM50097579((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MVZPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097579((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)copy SMILEScopy InChI
Affinity DataEC50:  4.40nMAssay Description:Displacement of [3H]DAMGO from human kappa opioid receptor expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765GQZPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097579((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)copy SMILEScopy InChI
Affinity DataEC50:  4.40nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in CHO cells assessed as inhibition of U50488-stimulated [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208663GPubMed