Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50297170'
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Displacement of [3H]diprenorphine from k-Y312A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1K9DPubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)copy SMILEScopy InChI
Affinity DataKi:  292nMAssay Description:Displacement of [3H]diprenorphine from k-E297A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1K9DPubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)copy SMILEScopy InChI
Affinity DataKi:  488nMAssay Description:Displacement of [3H]diprenorphine from opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1K9DPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)copy SMILEScopy InChI
Affinity DataKi:  588nMAssay Description:selective binding affinity against kappa opioid receptor, using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1K62PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)copy SMILEScopy InChI
Affinity DataKi:  588nMAssay Description:Displacement of [3H]U69493 from Hartley guinea pig kappa opioid receptor by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154H3QPubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1 from mouse brain membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2T7RPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+3nMAssay Description:The compound tested for agonistic activity against Opioid receptor kappa 1 as the [3H]- U-69,594 radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53M9PubMed