Found 31 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50381677' 
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]U-69593 from human recombinant Opioid receptor kappa 1 on CHO cell membranes.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of radiolabeled U69593 from kappa1 opioid receptor in Hartley guinea pig brainMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Displacement of [3H]U-69593 from kappa-opoid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.970nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 0.970nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig brain membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor transfected in CHO cell membranes after 60 minsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]U-69593 from guinea pig cerebellum KORMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]U69593 from human KOP receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]U69,593 from human recombinant opioid kappa receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in CHO cells membrane after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Binding affinity at Opioid receptor kappa 1 by displacement of [3H]U-69593 in guinea pig brain membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Universit£ di Chieti-Pescara"G. d'Annunzio"
Curated by ChEMBL
Universit£ di Chieti-Pescara"G. d'Annunzio"
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration against Opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky
Curated by ChEMBL
University of Kentucky
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Tested for inhibitory concentration against [3H]U-69593 binding at sites of kappa-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]naloxone from kappa opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Stimulation of U-69,593 binding at human recombinant Opioid receptor kappa 1 transfected into CHO cells.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Universit£ di Chieti-Pescara"G. d'Annunzio"
Curated by ChEMBL
Universit£ di Chieti-Pescara"G. d'Annunzio"
Curated by ChEMBL
Affinity DataEC50: 7.70nMAssay Description:Agonist activity at rat kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Agonist activity at recombinant kappa-opioid receptor in human HEK293 cells by [35S]-GTP-gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at human KOR expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 207nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK-293 cells assessed as stimulation of [35S]-GTPgammaS binding after 30 mins by liquid...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Agonist activity at human kappa opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins by ...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells after 2 hrs by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells assessed as caclium mobilization after 1 hrs by fluorescence analy...More data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 534nMAssay Description:Agonist activity at GFP-fused kappa opioid receptor (unknown origin) expressed in HEK293 cells assessed as recruitment of beta-arrestin-2 after 10 mi...More data for this Ligand-Target Pair
