Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50399882'
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399882(CHEMBL2180638)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X58ZXPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399882(CHEMBL2180638)copy SMILEScopy InChI
Affinity DataEC50:  37nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HN9PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399882(CHEMBL2180638)copy SMILEScopy InChI
Affinity DataEC50:  449nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as increase in beta-arrestin 2 recruitmentMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HN9PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399882(CHEMBL2180638)copy SMILEScopy InChI
Affinity DataEC50:  35nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X58ZXPubMed