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TargetKappa-type opioid receptor [Y312A](Homo sapiens (Human))
University of North Carolina School of Medicine
University of North Carolina School of Medicine
Affinity DataKi: 390nM ΔG°: -36.6kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor [Y312A](Homo sapiens (Human))
University of North Carolina School of Medicine
University of North Carolina School of Medicine
Affinity DataEC50: 360nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
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