Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with Target = 'KiSS-1 receptor' and Ligand = 'BDBM26349'
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataKi:  0.0390nMAssay Description:Binding affinity to human KISS1R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M675SPubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataKi:  0.0570nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M675SPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Displacement of [125]metastin from metastin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2P0KPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataIC50: 0.0820nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP477RPubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP477RPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K07586PubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataIC50: 8.51E+3nMAssay Description:Inhibition of human KISS1R expressed in CHO cells assessed as inhibition of KISS1R-mediated cell growth after 4 days by cell counting kit-8 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M675SPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataEC50:  0.0490nMAssay Description:Agonist activity at human KISS1R assessed as induction of intracellular calcium mobilization by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP477RPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataEC50:  17.3nMAssay Description:Activity at metastin receptor expressed in HEK293 cells by measuring calcium releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2P0KPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataEC50:  0.0650nMAssay Description:Agonist activity at human OT7T175 assessed as increase in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7PJTPubMed