Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'KiSS-1 receptor' and Ligand = 'BDBM50320821'
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50320821(CHEMBL1163809 | N-(4-(3-(3-aminopropanamido)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]metastin(40-54) from human GPR54 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22807S6PubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50320821(CHEMBL1163809 | N-(4-(3-(3-aminopropanamido)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RHMPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50320821(CHEMBL1163809 | N-(4-(3-(3-aminopropanamido)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human GPR54 receptor expressed in CHO cells assessed as inhibition of metastin(40-54)-induced intracellular calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22807S6PubMed