Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM50324539'
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
University of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Inhibition of human recombinant MBP-KAT2 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58N6PubMedMMDB
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
University of Piemonte Orientale Amedeo Avogadro

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KAT2 in human prefrontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58N6PubMedMMDB
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Rattus norvegicus)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat KAT-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Rattus norvegicus)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat brain KAT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58N6PubMed