Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Kynurenine 3-monooxygenase' and Ligand = 'BDBM50237999'
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50237999(CHEMBL4064834)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant full-length human N-terminal GST tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using L-kynurenine ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0W54PubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50237999(CHEMBL4064834)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:Compound was tested for binding affinity towards opioid receptor delta 1 by displacing [3H]DPDPE radioligand in rat brain P2 synaptosomes membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0W54PubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50237999(CHEMBL4064834)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Binding affinity for DA transporter using [125I]RTI-55 in frozen rat caudate membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0W54PubMed