Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase A chain' and Ligand = 'BDBM50546964'
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50546964(CHEMBL4787940 | US11247971, Cmpd ID 401)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KJ6PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50546964(CHEMBL4787940 | US11247971, Cmpd ID 401)copy SMILES
Affinity DataIC50: 119nMAssay Description:Inhibition of GS[HiBiT]GS-tagged LDHA (unknown origin) expressed in HEK-293T cells measured after 1 hr by CESTAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KJ6PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50546964(CHEMBL4787940 | US11247971, Cmpd ID 401)copy SMILES
Affinity DataIC50: 450nMAssay Description:Inhibition of LDHA in human MIA PaCa-2 cells assessed as decrease in lactate production incubated for 2 hrs by lactate oxidase-coupled fluorescence b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KJ6PubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50546964(CHEMBL4787940 | US11247971, Cmpd ID 401)copy SMILES
Affinity DataIC50: 505nMAssay Description:Inhibition of LDHA in human A673 cells assessed as decrease in lactate production incubated for 2 hrs by lactate oxidase-coupled fluorescence based a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057KJ6PubMed