Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase A chain' and Ligand = 'BDBM50546973'
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50546973(CHEMBL4782843 | US11247971, Cmpd ID 258)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50546973(CHEMBL4782843 | US11247971, Cmpd ID 258)copy SMILES
Affinity DataIC50: 112nMAssay Description:Inhibition of GS[HiBiT]GS-tagged LDHA (unknown origin) expressed in HEK-293T cells measured after 1 hr by CESTAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50546973(CHEMBL4782843 | US11247971, Cmpd ID 258)copy SMILES
Affinity DataIC50: 333nMAssay Description:Inhibition of LDHA in human MIA PaCa-2 cells assessed as decrease in lactate production incubated for 2 hrs by lactate oxidase-coupled fluorescence b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50546973(CHEMBL4782843 | US11247971, Cmpd ID 258)copy SMILES
Affinity DataIC50: 509nMAssay Description:Inhibition of LDHA in human A673 cells assessed as decrease in lactate production incubated for 2 hrs by lactate oxidase-coupled fluorescence based a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50546973(CHEMBL4782843 | US11247971, Cmpd ID 258)copy SMILES
Affinity DataKd:  0.0193nMAssay Description:Binding affinity to human His-tagged LDHA by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB