Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase B chain' and Ligand = 'BDBM50052254'
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

LigandPNGBDBM50052254(2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95800PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

LigandPNGBDBM50052254(2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XV9PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

LigandPNGBDBM50052254(2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P46PubMed