Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'LIM domain kinase 1' and Ligand = 'BDBM13216'
TargetLIM domain kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 59nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F193Q2PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 86nMMore data for this Ligand-Target Pair
In DepthDetails
TargetLIM domain kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z15R6PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F193Q2PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F193Q2PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataKd:  570nMAssay Description:Binding constant for LIMK1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataKd:  570nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22F7KSQPCBioAssay
TargetLIM domain kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataKd:  570nMAssay Description:Binding constant for full-length LIMK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed