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Affinity DataIC50: 116nMAssay Description:Inhibition of Candida albicans ATCC SC5314 CYP51 incubated for 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 127nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005 (experiment 2)More data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:Inhibition of CYP51 in Candida albicans ATCC SC5314 measured after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 137nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005 (experiment 1)More data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 137nMAssay Description:In vitro inhibition of Lanosterol 14-alpha demethylase (Candida albicans CY1005)More data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataKd: 1.20E+5nMAssay Description:Binding affinity to human CYP51More data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataKd: 4.00E+4nMAssay Description:Binding affinity to human His-tagged CYP51 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Nippon Roche Research Center
Curated by ChEMBL
Nippon Roche Research Center
Curated by ChEMBL
Affinity DataKd: 7.00E+4nMAssay Description:Binding affinity to human CYP51More data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Swansea University
Curated by ChEMBL
Swansea University
Curated by ChEMBL
Affinity DataKd: 200nMAssay Description:Binding affinity to Mycobacterium tuberculosis CYP51More data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Swansea University
Curated by ChEMBL
Swansea University
Curated by ChEMBL
Affinity DataKd: 3.00E+4nMpH: 7.5 T: 2°CAssay Description:The assay was developed based on the optical spectral property of P450 enzyme to elicit both type I and type II spectral changes (350 nm through 450 ...More data for this Ligand-Target Pair
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