Found 3 Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM50398675' TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech, Inc.
US Patent
Genentech, Inc.
US Patent
Affinity DataKi: 2nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech, Inc.
US Patent
Genentech, Inc.
US Patent
Affinity DataKi: 4nMAssay Description:Inhibition of LRRK2 using FAM-LRRKtide as substrate after 120 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech, Inc.
US Patent
Genentech, Inc.
US Patent
Affinity DataIC50: 24nMAssay Description:Inhibition of autophosphorylation of LRRK2 in human HEK293 cellsMore data for this Ligand-Target Pair
