Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Leukotriene C4 synthase' and Ligand = 'BDBM223263'
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223263(2-(5-((Cyclopropylmethyl)(1,2-dihydroacenaphthylen...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NPGUS Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
ASTRAZENECA AB

US Patent
LigandPNGBDBM223263(2-(5-((Cyclopropylmethyl)(1,2-dihydroacenaphthylen...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66JN5US Patent