Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Leukotriene C4 synthase' and Ligand = 'BDBM50519570'
TargetLeukotriene C4 synthase(Homo sapiens (Human))
Orexo AB

Curated by ChEMBL
LigandPNGBDBM50519570(CHEMBL4567083)copy SMILEScopy InChI
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human N-terminal His6-tagged LTC4S expressed in Pichia pastoris X33 using LTA4 methyl ester and glutathione as substrate preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8XMWPubMed
TargetLeukotriene C4 synthase(Homo sapiens (Human))
Orexo AB

Curated by ChEMBL
LigandPNGBDBM50519570(CHEMBL4567083)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of LTC4S in zymosan-stimulated human PBMC assessed as inhibition of LTC4 production preincubated for 45 mins followed by zymosan stimulati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8XMWPubMed