Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4C' and Ligand = 'BDBM191599'
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM4C (1 to 349 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP5559PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM191599(KDOAM-21 | ethyl 2-(((2-((2-(dimethylamino)ethyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2288PubMed