Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5B' and Ligand = 'BDBM50158693'
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158693(CHEMBL3787133 | US10273222, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal His-FLAG-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected sf9 cells using biotin-H3K4me3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP5559PubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158693(CHEMBL3787133 | US10273222, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6THRUS Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50158693(CHEMBL3787133 | US10273222, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDM5B in human ZR-75-1 cells assessed as reduction in H3K4me3 demethylation incubated for 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP5559PubMed