Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM501809'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM501809(4-[6-(4-amino-piperidin-1-yl)-4- methyl-5-oxo-3-p...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P33PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM501809(4-[6-(4-amino-piperidin-1-yl)-4- methyl-5-oxo-3-p...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of LSD1 in human THP1 cells assessed as induction of cell differentiation by measuring CD11b expression incubated for 96 hrs by FACS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4P33PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM501809(4-[6-(4-amino-piperidin-1-yl)-4- methyl-5-oxo-3-p...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V127ZXUS Patent